Anabolic steroids are synthetic derivatives of clinical effects and side effects demonstratethe androgenic properties of this class of drugs. Was not achieved complete dissociation of anabolic and androgenic effects. The actions of anabolic steroids are therefore similar to those of male sex hormones with the possibility of serious disturbances of growth and sexual development if given to young children. Anabolic steroids suppress gonadotropic functions of the pituitary and may exert a direct effect on the testes. During exogenous administration of anabolic androgens,
endogenous testosterone release is inhibited by inhibition of the pituitary luteinizing hormone (LH). In large doses, spermatogenesis may be suppressed through feedback inhibition of pituitary follicle stimulating hormone (FSH).
Anabolic steroids have been reported to increase low-density lipoproteins and high-density lipoproteins. This return to normal levels after discontinuation of treatment.