To strengthen the anabolic properties of testosterone, more than 100 synthetic steroid derivatives have been described for human purposes. The anabolic effect promotes protein synthesis, muscle growth and erythropoiesis. In clinical practice, substances with anabolic effect are needed to overcome various catabolic states. However, none of these compounds are devoid of androgenicity. Androgenic and anabolic properties of anabolic steroids cannot be totally separated. Therefore, it is more appropriate to use the term anabolic androgenic steroids (AAS).
Anavar was developed to treat conditions of muscle wasting and rapid weight loss, as is a common reason for inception with any anabolic steroid. Developed in 1964, by Searle Laboratories to treat such conditions, Searle is no longer in existence as it was bought and absorbed into Pfizer in 2003. However, it was Searle’s development of Anavar that is of importance because this is a pharmacy that has brought us some of the most well-known medications and other items we still use today, most notably, Celebrex, Ambien, Dramamine and NutraSweet. As you can see Searle developed some very important products over the years and its development of Anavar is no exception because with its inception one of the safest anabolic steroids for both men and women would hit the shelves.
Testosterone Propionate Many consider propionate to be the mildest testosterone ester, and the preferred form for the dieting/cutting phases of training. Some will go so far as to say that propionate will harden the physique, while giving the user less water and fat retention than one typically expects to see with a testosterone.
During a typical cycle one will see action that is consistent with a testosterone. Users sensitive to gynecomastia and water retention may therefore need to add an anti-estrogen like Arimidex, Femara or Aromasin. Those particularly troubled by gynecomastia may find that a combination of Nolvadex and Proviron works especially well at preventing/halting this occurrence.