Most drugs of abuse are addictive. Addiction is a chronic, relapsing disease characterized by compulsive drug seeking and use despite negative consequences and by long-lasting changes in the brain. People who are addicted have strong cravings for the drug, making it difficult to stop using. Most drugs alter a person’s thinking and judgment, which can increase the risk of injury or death from drugged driving or infectious diseases (., HIV/AIDS, hepatitis) from unsafe sexual practices or needle sharing. Drug use during pregnancy can lead to neonatal abstinence syndrome, a condition in which a baby can suffer from dependence and withdrawal symptoms after birth. Pregnancy-related issues are listed in the chart below for drugs where there is enough scientific evidence to connect the drug use to negative effects. However, most drugs could potentially harm an unborn baby.
Hippocrates described a syndrome of wasting and progressive inanition among patients who were ill and dying. Derived from the Greek words kakos, meaning “bad things,” and hexus, meaning “state of being,” the term cachexia has been used to describe weight loss. From an, meaning “without,” and orexis, meaning “appetite, desire,” the word anorexia is used to characterize loss of appetite. Cachexia, a hypercatabolic state that is defined by an accelerated loss of skeletal muscle in the context of a chronic inflammatory response, is best described in the setting of cancer but is also seen in other advanced chronic illnesses including AIDS, heart failure, and chronic obstructive pulmonary disease (COPD) [ 1 ]. Although body composition changes are not identical in all of these disease states, the term cachexia is used in all of these settings.
Pharmacom Labs Oxandrolonos is presented in a 100 tablet box with 2 blister packs of 50 tablets each. Each tablet reportedly contains 10 milligrams of oxandrolone according to the label and packaging. Samples of this product were purchased from a North American-based authorized distributor between the dates of June 1, 2015 and June 30, 2015. The samples were forwarded and received by the analytical laboratory SIMEC AG for HPLC-UV testing on July 20, 2015. The quantitative dosage testing report was completed on August 10, 2015. The product was identified with an expiration date of October 15, 2018 and a batch number of MBMN1. There was no verification code printed on the box.