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Michel Jouvet, an emeritus experimental medicine professor and neurophysiologist at Lafon Laboratories in France, was the primary developer of the drug. Development started back in the late seventies after a series of benzhydral sulfinyl compounds were invented. These, including adrafinil, were used experimentally to treat narcolepsy in 1986. Since it was the main metabolite of adrafinil, Modafinil came on the market. Since it lacked the –OH group on the last amide, it had greater use than adrafinil. It has been available on the market in France as Modiodal since 1994.

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