Varicose veins and spider veins typically occur on the legs, although any body site can be affected. In one study, almost 50 percent of women between 40 and 50 years of age, and nearly 75 percent of women between 60 and 70 years of age were found to have varicose veins. Varicose veins are also a common problem for many men. Approximately 25 percent of men 30 to 40 years of age and almost 50 percent of men age 70 and older are estimated to have varicose veins. These non-functional blood vessels are not just a cosmetic nuisance; nearly half of all patients who seek treatment do so because of pain and discomfort.
In January 2004, Major League Baseball announced a new drug policy which originally included random, offseason testing and 10-day suspensions for first-time offenders, 30-days for second-time offenders, 60-days for third-time offenders, and one year for fourth-time offenders, all without pay, in an effort to curtail performance-enhancing drug use (PED) in professional baseball. This policy strengthened baseball's pre-existing ban on controlled substances , including steroids, which has been in effect since 1991.  The policy was to be reviewed in 2008, but under pressure from the . Congress , on November 15, 2005, players and owners agreed to tougher penalties; a 50-game suspension for a first offense, a 100-game suspension for a second, and a lifetime ban for a third.